{"id":7796,"date":"2026-05-07T09:19:54","date_gmt":"2026-05-07T09:19:54","guid":{"rendered":"https:\/\/asianvenousacademy.org\/?p=7796"},"modified":"2026-05-07T09:46:15","modified_gmt":"2026-05-07T09:46:15","slug":"european-update-french-medicines-agency-reissues-safety-warning-on-sclerotherapy-for-varicose-veins","status":"publish","type":"post","link":"https:\/\/asianvenousacademy.org\/zh\/european-update-french-medicines-agency-reissues-safety-warning-on-sclerotherapy-for-varicose-veins\/","title":{"rendered":"European Update | French Medicines Agency Reissues Safety Warning on Sclerotherapy for Varicose Veins"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><div class=\"vc_row wpb_row vc_row-fluid vc_custom_1459508073015\"><div class=\"wpb_column vc_column_container vc_col-sm-12 vc_col-lg-9 vc_col-md-9\"><div class=\"vc_column-inner vc_custom_1452702342137\"><div class=\"wpb_wrapper\"><div class=\"vc_custom_heading no_stripe text_align_left\" ><h2 style=\"text-align: left\" class=\"consulting-custom-title\">European Update | French Medicines Agency Reissues Safety Warning on Sclerotherapy for Varicose Veins<\/h2><\/div>\n\t<div  class=\"wpb_single_image wpb_content_element vc_align_left wpb_content_element\">\n\t\t\n\t\t<figure class=\"wpb_wrapper vc_figure\">\n\t\t\t<div class=\"vc_single_image-wrapper   vc_box_border_grey\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1362\" src=\"https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-scaled.png\" class=\"vc_single_image-img attachment-full\" alt=\"\" title=\"article\" srcset=\"https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-scaled.png 2560w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-300x160.png 300w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-1024x545.png 1024w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-768x409.png 768w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-1536x817.png 1536w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-2048x1090.png 2048w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-900x479.png 900w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/article-600x319.png 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><\/div>\n\t\t<\/figure>\n\t<\/div>\n\n\t<div class=\"wpb_text_column wpb_content_element vc_custom_1778145804835\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>The French National Agency for the Safety of Medicines and Health Products (ANSM) has recently reissued an official safety communication regarding the use of venous sclerosants in the treatment of varicose veins. The agency emphasized that serious cardiovascular adverse events continue to be reported following sclerotherapy procedures, including deep vein thrombosis (DVT), pulmonary embolism (PE), and cardiac arrhythmias, some of which may be life-threatening.<\/p>\n<p>The sclerosants most commonly used in France currently include\u00a0<em>Aetoxiscl\u00e9rol<\/em>\u00a0and\u00a0<em>Fibrovein<\/em>. According to ANSM, these agents remain under enhanced pharmacovigilance monitoring. Despite multiple rounds of safety communications, updated prescribing information, and educational initiatives, reports continue to emerge involving:<\/p>\n<ul>\n<li>Severe cardiovascular complications<\/li>\n<li>Inappropriate use in patients with contraindications<\/li>\n<li>Errors in drug preparation and injection procedures<\/li>\n<\/ul>\n<p>Among these concerns, risk management associated with foam sclerotherapy has become one of the major focuses of current regulatory oversight.<\/p>\n\n\t\t<\/div>\n\t<\/div>\n\n\t<div  class=\"wpb_single_image wpb_content_element vc_align_left wpb_content_element\">\n\t\t\n\t\t<figure class=\"wpb_wrapper vc_figure\">\n\t\t\t<div class=\"vc_single_image-wrapper   vc_box_border_grey\"><img loading=\"lazy\" decoding=\"async\" width=\"1661\" height=\"947\" src=\"https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic.png\" class=\"vc_single_image-img attachment-full\" alt=\"\" title=\"pic\" srcset=\"https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic.png 1661w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic-300x171.png 300w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic-1024x584.png 1024w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic-768x438.png 768w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic-1536x876.png 1536w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic-900x513.png 900w, https:\/\/asianvenousacademy.org\/wp-content\/uploads\/2026\/05\/pic-600x342.png 600w\" sizes=\"(max-width: 1661px) 100vw, 1661px\" \/><\/div>\n\t\t<\/figure>\n\t<\/div>\n\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h2 class=\"wp-block-heading\">Key Recommendations from French Regulators<\/h2>\n<p>ANSM stressed that physicians must conduct comprehensive pre-procedural evaluations before performing sclerotherapy. Particular attention should be paid to:<\/p>\n<ul>\n<li>Thromboembolic risk factors<\/li>\n<li>Cardiovascular history<\/li>\n<li>Migraine and patent foramen ovale (PFO)-related risks<\/li>\n<li>Diabetes mellitus<\/li>\n<li>Obesity<\/li>\n<li>Smoking status and other vascular risk factors<\/li>\n<\/ul>\n<p>In addition, the agency emphasized several mandatory safety measures:<\/p>\n<ul>\n<li>Patients must receive comprehensive informed consent regarding procedural risks<\/li>\n<li>Treatment facilities should be equipped with emergency resuscitation equipment and defibrillators<\/li>\n<li>Post-procedural observation is recommended<\/li>\n<li>Healthcare professionals involved in treatment should receive cardiopulmonary resuscitation (CPR) training<\/li>\n<\/ul>\n<p>Regulators also highlighted the importance of recognizing warning symptoms that may indicate severe complications, including:<\/p>\n<ul>\n<li>Chest pain<\/li>\n<li>Dyspnea<\/li>\n<li>Palpitations<\/li>\n<li>Syncope<\/li>\n<li>Neurological symptoms<\/li>\n<li>Calf pain, swelling, or erythema<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Implications for the International Venous Community<\/h2>\n<p>The Asian Venous Academy (AVA) believes that this latest regulatory update from France serves as another important reminder to the global venous medicine community that \u201cminimally invasive\u201d does not mean \u201crisk-free.\u201d<\/p>\n<p>Sclerotherapy has been widely adopted because of its convenience, outpatient applicability, and minimally invasive nature. However, any pharmacological intervention involving the vascular system may carry systemic risks. This is particularly relevant in foam sclerotherapy, where interactions among sclerosant agents, gas composition, and venous hemodynamics require meticulous standardization and procedural control.<\/p>\n<h2 class=\"wp-block-heading\">Increasing Importance of Patient Selection and Hemodynamic Assessment<\/h2>\n<p>As venous disease management evolves globally from a strategy focused primarily on eliminating visible varicosities toward long-term hemodynamic management, the importance of comprehensive pre-treatment assessment continues to increase.<\/p>\n<p>Key considerations now include:<\/p>\n<ul>\n<li>Deep venous system evaluation<\/li>\n<li>Thrombotic risk stratification<\/li>\n<li>Iliac venous outflow assessment<\/li>\n<li>Overall circulatory and hemodynamic status of the patient<\/li>\n<\/ul>\n<p>This transition reflects a broader shift in modern venous medicine toward individualized and physiology-oriented treatment strategies.<\/p>\n<h2 class=\"wp-block-heading\">Venous Medicine Is Entering the Era of Safety and Long-Term Outcomes<\/h2>\n<p>Over the past decade, the field of varicose vein treatment has experienced rapid technological advancement, with numerous minimally invasive techniques emerging worldwide.<\/p>\n<p>Today, however, international regulatory trends are increasingly emphasizing:<\/p>\n<ul>\n<li>Long-term safety outcomes<\/li>\n<li>Real-world complication data<\/li>\n<li>Standardized physician training<\/li>\n<li>Protocol-driven procedural practice<\/li>\n<\/ul>\n<p>These developments suggest that the future of venous medicine will no longer be defined solely by faster or less invasive interventions, but increasingly by safer, more sustainable, and hemodynamically sound treatment approaches.<\/p>\n<p>In the context of the rapidly evolving global venous field, patient safety and hemodynamic principles are expected to become increasingly central to the future direction of international venous medicine.<\/p>\n<p><strong>Source:<\/strong>\u00a0<a href=\"https:\/\/www.univadis.fr\/index.php\/viewarticle\/scl%25C3%25A9rosants-veineux-attention-aux-effets-2026a10007zl\">French National Agency for the Safety of Medicines and Health Products (ANSM) official safety communication on venous sclerosants.<\/a><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"post_bottom_wr \">\n    <div class=\"post_bottom media\">\n\t<div class=\"tags media-body\"><a href=\"https:\/\/asianvenousacademy.org\/zh\/tag\/varicose-veins\/\" rel=\"tag\">Varicose Veins<\/a> <a href=\"https:\/\/asianvenousacademy.org\/zh\/tag\/venous-disease\/\" rel=\"tag\">Venous Disease<\/a><\/div>\t<\/div><\/div>    <div class=\"stm_post_comments\">\n            <\/div>\n<\/div><\/div><\/div><div class=\"wpb_column vc_column_container vc_col-sm-3 vc_hidden-sm vc_hidden-xs\"><div class=\"vc_column-inner \"><div class=\"wpb_wrapper\">\n<div class=\"stm_sidebar\">\n\n            <style type=\"text\/css\" scoped>\n            .vc_custom_1452662185213{margin-bottom: 40px 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alt=\"{&quot;ARInfo&quot;:{&quot;IsUseAR&quot;:false},&quot;Version&quot;:&quot;1.0.0&quot;,&quot;MakeupInfo&quot;:{&quot;IsUseMakeup&quot;:false},&quot;FaceliftInfo&quot;:{&quot;IsChangeEyeLift&quot;:false,&quot;IsChangeFacelift&quot;:false,&quot;IsChangePostureLift&quot;:false,&quot;IsChangeNose&quot;:false,&quot;IsChangeFaceChin&quot;:false,&quot;IsChangeMouth&quot;:false,&quot;IsChangeThinFace&quot;:false},&quot;BeautyInfo&quot;:{&quot;SwitchMedicatedAcne&quot;:false,&quot;IsAIBeauty&quot;:false,&quot;IsBrightEyes&quot;:false,&quot;IsSharpen&quot;:false,&quot;IsOldBeauty&quot;:false,&quot;IsReduceBlackEyes&quot;:false},&quot;HandlerInfo&quot;:{&quot;AppName&quot;:2},&quot;FilterInfo&quot;:{&quot;IsUseFilter&quot;:false}}\" title=\"Pic2\" \/><\/a><\/li><\/ul><\/div>\n\t\t<\/div> \n\t<\/div> <div class=\"vc_wp_text wpb_content_element\"><aside class=\"widget widget_text\"><h5 class=\"widget_title\">Advancing Hemodynamic Innovation<\/h5>\t\t\t<div class=\"textwidget\"><p><strong>Bridging the gap between pioneering theory and clinical mastery.<\/strong><\/p>\n<p>Asian Venous Academy serves as the premier hub for hemodynamic education in Asia. By integrating traditional wisdom with modern innovations\u2014such as AI-assisted diagnostics and functional preservation surgery\u2014we empower clinicians to deliver precise, science-based treatments for venous diseases.<\/p>\n<\/div>\n\t\t<\/aside><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner \"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div>\n<\/div>    \n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner \"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><div data-vc-full-width=\"true\" data-vc-full-width-temp=\"true\" data-vc-full-width-init=\"false\" class=\"vc_row wpb_row vc_row-fluid third_bg_color vc_custom_1459505959648\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner \"><div class=\"wpb_wrapper\">\n<section class=\"vc_cta3-container\" >\n    <div class=\"vc_general vc_cta3 third_bg_color vc_cta3-style-flat vc_cta3-shape-square vc_cta3-align-left vc_cta3-color-classic vc_cta3-icon-size-md vc_cta3-actions-right vc_custom_1768829984189 style=\"\"\">\n                        <div class=\"vc_cta3_content-container\">\n                                    <div class=\"vc_cta3-content\">\n                <header class=\"vc_cta3-content-header\">\n                    <div class=\"vc_custom_heading text_align_left\" ><h2 style=\"font-size: 20px;color: #ffffff;line-height: 24px;text-align: left\" class=\"consulting-custom-title\">Interested in academic collaboration with AVA?<\/h2><\/div>                                    <\/header>\n                            <\/div>\n                        <div class=\"vc_cta3-actions\"><div class=\"vc_btn3-container vc_btn3-right vc_do_btn\" ><a class=\"vc_general vc_btn3 vc_btn3-size-md vc_btn3-shape-rounded vc_btn3-style-flat vc_btn3-icon-right vc_btn3-color-theme_style_2\" href=\"#\" title=\"\">Contact the Academy <i class=\"vc_btn3-icon stm-location\"><\/i><\/a><\/div><\/div>        <\/div>\n                    <\/div>\n<\/section><\/div><\/div><\/div><\/div><div class=\"vc_row-full-width vc_clearfix\"><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner \"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Recent safety updates issued by the French National Agency for the Safety of Medicines and Health Products (ANSM) have once again drawn international attention to the potential cardiovascular risks associated with sclerotherapy for varicose veins, particularly foam sclerotherapy. Despite longstanding enhanced pharmacovigilance measures, serious adverse events including deep vein thrombosis, pulmonary embolism, and cardiac arrhythmias continue to be reported. This regulatory update highlights the growing global emphasis on patient selection, hemodynamic assessment, procedural standardization, and long-term safety outcomes in modern venous medicine.<\/p>","protected":false},"author":1,"featured_media":7737,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[117],"tags":[118,131],"class_list":["post-7796","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-insights-news","tag-varicose-veins","tag-venous-disease"],"_links":{"self":[{"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/posts\/7796","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/comments?post=7796"}],"version-history":[{"count":5,"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/posts\/7796\/revisions"}],"predecessor-version":[{"id":7802,"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/posts\/7796\/revisions\/7802"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/media\/7737"}],"wp:attachment":[{"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/media?parent=7796"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/categories?post=7796"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/asianvenousacademy.org\/zh\/wp-json\/wp\/v2\/tags?post=7796"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}